Sexual Health
Patients can expect significant savings and better outcomes from their prescription medications when health care professionals use comparative effectiveness research, according to researchers at the University of Illinois at Chicago.
ZymoGenetics, Inc. (NASDAQ:ZGEN) announced that Interleukin 21 (IL-21) demonstrated an impressive overall response rate in the treatment of metastatic melanoma. In interim Phase 2 results from 24 patients, 29 percent showed a partial response, with an additional 33 percent of patients showing stable disease in this difficult to treat disease.
Alkermes, Inc. (NASDAQ: ALKS) announced the initiation of two new clinical trials of ALKS 33, an oral opioid modulator for the potential treatment of addiction and other nervous system disorders. Study ALK33-004 is a phase 1 clinical trial designed to examine the ability of ALKS 33 to block the effects of an opioid following a single oral dose of ALKS 33 in healthy, non-dependent, opioid-experienced subjects. Study ALK33-003 is a phase 1 clinical trial designed to evaluate the pharmacokinetics, safety and tolerability of multiple doses of ALKS 33 in healthy volunteers.
Analyzing MRI studies of the brain with software developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) may allow diagnosis of Alzheimer"s disease and of mild cognitive impairment, a lesser form of dementia that precedes the development of Alzheimer"s by several years. In their report that will appear in the journal Brain and has been released online, the MGH/Martinos team show how their software program can accurately differentiate patients with mild cognitive impairment or Alzheimer"s disease from normal elderly individuals based on anatomic differences in brain structures known to be affected by the disease.
HHS and the Department of Justice on Wednesday launched the Health Care Fraud Prevention and Enforcement Action Team to detect and prevent fraud in Medicare and Medicaid, the Washington Post reports (Johnson, Washington Post, 5/21). DOJ also plans to establish teams to address fraud in the Medicare Part D program and CHIP (Kennedy, AP/Houston Chronicle, 5/20). Wednesday"s announcement also included a recommendation by President Obama"s administration to include $311 million in the fiscal year 2010 budget to address health care fraud, which is a 50% increase from FY 2009. According to Attorney General Eric Holder, efforts to combat health care fraud will contribute to the administration"s health care overhaul plans (Clark/Weaver, McClatchy/Kansas City Star, 5/20). The task force, which will include HHS and DOJ staff members, law enforcement agents and prosecutors, will meet biweekly, CQ HealthBeat reports (Norman, CQ HealthBeat, 5/20). Under the plan, existing enforcement teams in Miami and Los Angeles will be expanded and new teams will be established in Houston and Detroit, where officials say suspicious billing patterns have emerged. In addition, the plan will set up task forces in 10 other major cities, which were not named (AP/Houston Chronicle, 5/20). The enforcement teams will increase site visits to durable medical equipment suppliers upon their enrollment. In addition, officials will expand training to help providers identify and prevent fraud or other mistakes (CQ HealthBeat, 5/20). The task force will use electronic claims data to detect "unusual billing problems," according to the Post (Washington Post, 5/21). HHS Secretary Kathleen Sebelius said the task force also intends to simplify billing systems and assist state officials in conducting Medicaid audits (CQ HealthBeat, 5/20). According to Holder, the joint task force will allow officials to share real-time intelligence data on health care fraud by monitoring claims payments, billing patterns and targeted surveillance (AP/Houston Chronicle, 5/20). Money
James Maki, the second person in the US to receive a face transplant, has been telling his story in the hope that it will encourage more people to
East African health officials on Tuesday met in Kisumu, Kenya, to examine integrating HIV/AIDS issues into transport policies in the region, Xinhua/CRI.com reports. The East African Community in a statement released ahead of the conference on Monday said that the meeting, which runs through Friday, brings together more than 100 stakeholders at the national and regional levels, including experts from national AIDS commissions, as well as representatives from transport, health, trade, immigration, gender and youth ministries. Representatives from Burundi, Kenya, Rwanda, Tanzania and Uganda are attending the conference. Other representatives include those from the Lake Victoria Basin Commission, Lake Victoria Fisheries Organization, USAID, the International Organization for Migration, the Port Management Association of Eastern and Southern Africa, East Africa Trade and Transport, and the East, Central and Southern African Health Community. Delegates from the EAC Regional Inter-Parliamentary Forum on Health, Population and Development also are attending.The meeting aims to promote improved regional coordination and quality of HIV services for at-risk populations by bringing together national and regional efforts along major land, sea, ocean and inland transport systems. It also will provide an update on studies conducted to determine HIV transmission modes in the region, as well as identity appropriate HIV/AIDS prevention, care, treatment and support initiatives for communities located on transit hubs and corridors. According to the EAC statement, the meeting will identify ways for the transport sector to work in partnership with various implementing partners and local communities to address HIV/AIDS (Xinhua/CRI.com, 5/19).
Singer Elton John on Tuesday at the 2009 Bio International Convention in Atlanta called for renewed efforts to fight HIV/AIDS, the Atlanta Journal-Constitution reports. John, founder of the Elton John AIDS Foundation, addressed an audience that included CEOs of organizations working to develop HIV/AIDS therapies and vaccines. He called on governments and institutions to increase their focus on education, especially among young people; access to medical treatment; and needle-exchange programs (Poole, Atlanta Journal-Constitution, 5/19)."There are long-standing stereotypes and prejudices that inhibit our efforts to combat AIDS," John said, adding, "I am asking for your leadership." According to John, CDC estimates that one in every three new HIV cases occurs among people younger than age 30, a statistic that he said has not received adequate attention. "It is unfathomable and unconscionable that we are not making a bigger effort to educate this demographic about HIV/AIDS with creative materials and up-to-date information," John said, adding, "Our failure to do so is costing lives" (Turner, AP/PennLive.com, 5/19). John also noted a recent report by the Kaiser Family Foundation, which found that the number of Americans who believe HIV/AIDS is an urgent health problem has declined to 6% currently from 44% in 1995. Bob McNally, CEO of GeoVax Labs, said John"s message is that "just not enough is being done" and that "people continue to die from the disease." He added that John "spurred the audience towards being advocates" (Atlanta Journal-Constitution, 5/20).
Although the number of blacks who are registered as organ donors in Michigan has increased in the last 15 years, many are still reluctant to be organ donors, the Detroit News reports. According to Remonia Chapman, director of Gift of Life Michigan"s minority organ tissue transplant education program, many blacks are hesitant to participate with the organ donor registry because they have inadequate access to health care.Chapman said that increased awareness and education about organ donation and the diseases that lead to the need for donated organs, as well as partnerships with minority donors, black ministers and community groups, have encouraged more blacks to be organ donors. In the last 15 years, the percentage of black Michigan residents who are registered organ donors has increased from 10.8% to 21%, with overall minority registration at 24%. Chapman noted that about 41.3% of people on Michigan"s transplant waiting list and about 46% of people in need of a kidney are minorities.According to the News, minority donors are the best matches for minority organ recipients because the genetic profiles of the donor and recipient will have more similarities. Chapman added that the best matches for kidney recipients are donors from the recipient"s family or from the recipient"s ethnic group if a family donor is not available (Stolarz, Detroit News, 5/19).
Scientists have uncovered how and why limbs are targeted by thalidomide - the drug that caused serious defects in babies whose mothers had taken it to relieve their morning sickness.
In an effort that will contribute to raising the quality of medicines in Peru and the surrounding region, the country"s National Center for Quality Control - the Centro Nacional de Control de Calidad (CNCC) - has attained internationally recognized ISO/IEC 17025:2005 accreditation for testing and calibration laboratories. This achievement is being celebrated today in Lima by the CNCC along with its partners who assisted the laboratory in achieving this accreditation, including the U.S. Agency for International Development (USAID) and the U.S. Pharmacopeial (USP) Convention, a scientific nonprofit organization that develops and disseminates standards for the identity, quality, purity, strength and consistency of medicines as well as dietary supplements and food ingredients.
In a move reflecting the rapid acceptance of Cook Medical"s advanced endogaft for thoracic aortic aneurysm worldwide, the company has received approval to market the Zenith TX2® TAA Endovascular Graft in Canada. Globally, the Zenith TX2 Endovascular Graft is now available in more than 60 markets, including the United States, Canada, the United Kingdom, European Union, Australia and others internationally.
Impax Laboratories, Inc. (NASDAQ: IPXL) confirmed that the U.S. Food and Drug Administration (FDA) has granted approval of the Company"s Abbreviated New Drug Application (ANDA) for generic versions of Precose® Tablets (acarbose), 25 mg, 50 mg and 100 mg strengths. Precose®, a Bayer HealthCare Pharmaceuticals product, is used in the management of type two diabetes mellitus.
Satoris, Inc., a California-based molecular diagnostics company, announced today the launch of three research-use tests - two panels of plasma biomarkers shown to be significant in the neurodegenerative disease process, and a dementia discrimination panel. Specifically for use by Alzheimer"s researchers and by pharmaceutical companies developing new Alzheimer"s therapies, the panels are available now as a testing service.
Molecular superfamily causes melanoma spread A superfamily of molecules holds the secret to the development and spread of melanoma - the deadliest form of skin cancer, revealed a study published in the British Journal of Cancer*.
New sequencing and analysis of six strains Chlamydia will result in improved diagnosis of the sexually transmitted infection. This study provides remarkable insights into a new strain of Chlamydia that was identified in Sweden in 2006 after spreading rapidly across the country by evading most established diagnostic tests.
A meta-analysis of five trials has shown that more intensive glucose control in type 2 diabetes leads to fewer heart attacks and heart disease events - but has no significant effect on stroke or mortality from all causes. The findings are reported in an Article in this week"s diabetes special issue of The Lancet, written by Dr Kausik Ray, University of Cambridge, UK, and colleagues.
Aerosol delivery of antibiotics via nanoparticles may provide a means to
Three quarters (75%) of women with BV (Bacterial Vaginosis) admit the condition has prevented them from getting intimate with their partner, according to a new survey by Balance ActivTM Vaginal Gel.1 Sufferers reveal BV affects their personal relationships more than any other aspect of their lives, with one in ten sufferers resorting to ending relationships as a result of the embarrassing symptoms.1
Toshiba America Medical Systems, Inc. introduces two advanced multi-detector CT systems, the Aquilion® Premium edition and the Aquilion CX edition. The Aquilion Premium rounds out the company"s CT portfolio to include a product with 160-detector rows and coverage up to 8 cm in a single rotation. This system is also field-upgradeable to an Aquilion ONE. The Aquilion CX is Toshiba"s next generation 64-detector row CT system featuring faster reconstruction standards with up to 28 images per second, Toshiba"s proven Quantum Advantage detector technology and a patient couch that can accommodate up to 660 lbs. The Aquilion Premium and Aquilion CX are both available now.
New research from the US suggests that people who drink from bottles made of polycarbonate plastic, such as that used to make hard-plastic
The performance of a new diagnostic test platform that rapidly identifies Staphylococcus aureus (S. aureus, "staph") bacteremia and determines antibiotic resistance or susceptibility in as little as five hours was presented at the 109th General Meeting of the American Society of Microbiology in Philadelphia, PA this week.
PolyMedix, Inc., an emerging biotechnology company developing acute care products for infectious diseases and acute cardiovascular disorders, has received a notice of no objection from Health Canada for the Company"s Clinical Trial Application ("CTA") for its defensin mimetic antibiotic compound, PMX-30063. This notice of no objection allows for the initiation of the second human clinical study in Canada. PMX-30063 is a defensin mimetic antibiotic compound, the first of an entirely new class of antibiotic drugs that is believed to work in such a way that makes bacterial resistance unlikely to develop.
Hospital facilities upgrades due for completion by June 2009. Measures to reduce and eventually eliminate mixed sex wards and washing facilities throughout Somerset"s 13 community hospitals are nearing completion. Last year the government pledged to reduce mixed sex accommodation throughout all England"s NHS hospitals. All hospitals have now stepped up their efforts to deliver this goal.
In a dramatic meeting today at the UNAIDS headquarters in Geneva, members of the International Treatment Preparedness Coalition (ITPC) and AIDS-Free World met with the leaders and approximately 100 staff members of UNAIDS and WHO to present ITPC"s latest Missing the Target report, Failing Women, Failing Children: HIV, Vertical Transmission and Women"s Health, which identifies the failure of the international community in preventing vertical transmission (also known as prevention of mother-to-child transmission or PMTCT).
In selecting a Supreme Court nominee, President Obama will have a more diverse pool of judges to choose from than his predecessors did, largely because the number of women on the federal bench has increased dramatically over the past two decades, the AP/Kansas City Star reports. Just two of the 110 justices that have served on the Supreme Court are women: former Justice Sandra Day O"Connor and current Justice Ruth Bader Ginsburg. Most of the candidates Obama is considering are women.According to the AP/Star, there are 212 full-time female judges serving in the federal courts, meaning that women make up more than one quarter of the federal judiciary. In contrast, there were about 40 female federal judges during the Reagan administration. In addition, women make up at least 40% of the judges on 22 of the 53 state supreme courts, another likely for nominees. The AP/Star reports that the increase in the number of female judges reflects the rise in the number of practicing female lawyers; women currently account for about one-third of lawyers and nearly half of all law school graduates. Marcia Greenberger, co-president of the National Women"s Law Center, said, "I wouldn"t say the doors have swung open as fully as we would like." She added, "Nonetheless, there are superb women in the judiciary, academia and private practice."The AP/Star also reports that Obama might seek to increase racial diversity on the Supreme Court, as only two of the 110 justices have been black men: current Justice Clarence Thomas and former Justice Thurgood Marshall. There has never been a Hispanic, Asian-American or American Indian justice (Sherman, AP/Kansas City Star, 5/20).
Canada has received new support to recruit some of its best minds in pediatric leukemia research, thanks to the Cole Foundation. The family foundation has generously pledged $2.5 million to support up-and-coming, Montreal-based researchers at the Universitç© de Montrç©al, McGill University and the Universitç© du Quç©bec"s Institut national de la recherche scientifique - Institut Armand-Frappier. The Cole Foundation investment will include:
The Senate on Thursday voted 86-3 to approve a $91.3 billion fiscal year 2009 supplemental war appropriations bill (HR 2346) that includes $1.5 billion for influenza pandemic preparedness, the AP/Detroit Free Press reports (Taylor, AP/Detroit Free Press, 5/21). The House already has approved a $96.7 billion version of the measure (H Res 434) (Sanchez, CongressDaily, 5/22). A conference committee to reconcile the two bills will not meet until after lawmakers return from the Memorial Day recess (Stanton/Dennis, Roll Call, 5/21). Senate Majority Leader Harry Reid (D-Nev.) said, "There are very few things that need to be worked out in conference" before the measure is passed (CongressDaily, 5/22).
Boxer Evander Holyfield will fight Sammy Retta on July 26 in Ethiopia in an effort to raise money for HIV/AIDS organizations, Reuters India reports. Event organizers hope to raise between $5 million and $10 million from the fight. "I continue to strive to be the very best, but what got me to come here is" HIV/AIDS, Holyfield said, adding, "If we don"t find a cure to this, we"ll be extinct." According to Everton Boland -- CEO of Golden Globe, which is promoting the fight -- a significant portion of money raised will go directly to organizations addressing HIV/AIDS. Organizers said that a group established by African first ladies is the only recipient selected to date but they are considering others (Malone, Reuters India, 5/20).
Pregnant women with low levels of vitamin D may be more likely to suffer from bacterial vaginosis (BV) - a common vaginal infection that increases a woman"s risk for preterm delivery, according to a University of Pittsburgh study. Available online and published in the June issue of the Journal of Nutrition, the study may explain why African-American women, who often lack adequate vitamin D, are three times more likely than white women to develop BV.
DePuy Mitek, Inc., a leading orthopaedics sports medicine company, announced that all of its QUICKANCHOR® Plus suture anchors for small joint repair are now available pre-loaded with ORTHOCORD®. ORTHOCORD is the only high-strength, partially absorbable orthopedic suture on the market designed to provide a supple solution for soft tissue fixation while maintaining strength and knot security. The QUICKANCHOR Plus small joint suture anchors with ORTHOCORD include the MINI, MINILOK™, MICRO and MICROFIX™ product families.
American Science and Engineering, Inc. (AS&E®) (NASDAQ: ASEI), a leading worldwide supplier of innovative X-ray detection solutions, announced that it has received a $25 million follow-on order for a Middle East client for multiple Z Portal® cargo and vehicle screening systems and OmniView™ Gantry cargo inspection system to protect critical infrastructure in the region. AS&E"s Z Portal and OmniView systems will scan vehicles and trucks entering a high-risk facility in the Middle East for explosive threats and contraband.
Americans trying to eat healthier are looking to nutrition labels to help make better choices at the grocery store. But consumers who take those labels at face value may find they"re not eating as healthy as they think.
Women who are at risk for heart disease and who are also experiencing menopause symptoms now have an added re - a highly specialized clinic in the Division of Cardiology at the Cedars-Sinai Heart Institute. The Advanced Preventive Women"s Clinic at the Women"s Heart Center recently opened and is offering comprehensive cardiac risk assessments designed specifically for women who are in menopause. The clinic also offers menopausal patients state-of-the-art screenings, as well as personalized medicine therapies and counseling, including high-risk hormone counseling.
Couples are being asked to replace their usual form of birth control with a new male contraceptive in a study to test its effectiveness.
Diagnostic companies looking for growth in a tough economy can still find a vibrant market for their products in China, says a leading healthcare market research publisher. IVD markets in China will grow to more than $1.5 billion in 2009, making it the world"s sixth largest IVD market. The last few years have seen market growth of 15-20%. With about 575 new hospitals opening each year and a government plan to open more than 20,000 health clinics, the lab market is booming, according to a new report, "Who is Who in Clinical Diagnostics in China (Manufacturers and Distributors Profiles, Market, Industry Overview)," from Kalorama Information, in partnership with IVD market research firm McEvoy & Farmer.
Amid all the speculation over what course the Swine Flu epidemic will take, Boston-based biotech firm Replikins Ltd. last week analyzed the most recent peptide genomic sequence data available and determined that the infectivity of the H1N1 virus will increase markedly, while its lethality will remain relatively low for the immediate future.
The largest study of its kind to date shows that women may not be able to learn as well shortly before menopause compared to other stages in life. The research is published in the May 26, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.
An international research collaboration coordinated by UCD researchers and involving scientists at 21 institutes including the genome sequencing centres in the Wellcome Trust Sanger Institute, UK and the Broad Institute at MIT and Harvard, USA have defined six new genome sequences in the Candida fungus family and identified genetic differences in species that cause disease.
UroToday.com - Angiogenesis is the process of new blood vessel formation in tumors, facilitating their growth. Endostatin is a cleavage product of collagen and is a potent inhibitor of endothelial cell proliferation and migration. Endostatin causes apoptosis in endothelial and tumor cells. Prostate cancer expresses angiogenic factors.
For the second year in a row, the American Red Cross is encouraging loyal NASCAR fans to donate blood through the Red Cross by joining Red Cross Racing.
National guidelines are needed for timely disclosure of medical errors and informing patients, write Toronto-based researchers in a review http://www.cmaj.ca/press/pg1125.pdf in CMAJ (http://www.cmaj.ca).
Statement of Charles D. Connor, American Lung Association President and CEO:
As thousands of students nationwide prepare to leave high school, a UC Davis study appearing online in the June issue of the medical journal Pediatrics shows a clear link between attention problems early in school - as early as kindergarten - and lower high school test scores.
The Rural Doctors Association of Australia (RDAA) says two country doctors" skills last Friday-in saving
Swinging the club on the open green, hitting the perfect shot and playing in the warm sun are just a few things golfers love about hitting the links. Golfing can be a treat for both the mind and body. However, an injury to the bones, muscles or joints can cast a big shadow over the day. That is why the American Academy of Orthopaedic Surgeons (AAOS) recommends following the proper techniques to prevent golf-related injuries.
The Government today responded to the independent inquiry into contaminated blood supplies in the 1970s and 1980s.
Matrox Graphics Inc., the leading manufacturer of specialized graphics solutions, announced that QUBYX has integrated DATACOLOR"s Spyder3 colorimeter into its PerfectLUM medical display calibration software. In addition, the calibration software will also support the Matrox Xenia(tm) Series onboard 13-bit Gamma and Digital Luminance Correction (DLC(tm)) technology. By combining each company"s extensive and high quality solutions, Matrox has created a comprehensive package for the medical display and imaging marketplace that will ultimately save time, money, and improve efficiencies in patient care.
Health and Human Services Secretary Kathleen Sebelius announced today that the Department of Health and Human Services (HHS) is joining the Ad Council and Sesame Workshop, the nonprofit educational organization behind Sesame Street, to launch a national public service advertising campaign designed to encourage American families and children to take steps to protect themselves from the 2009 H1N1 flu virus and continue to practice healthy habits. As part of HHS and the Ad Council"s campaign, Sesame Workshop produced a television PSA featuring Sesame Street"s Elmo and Gordon explaining the importance of healthy habits such as washing your hands, avoid touching your eyes, nose and mouth and sneezing into the bend of your arm.
American climber Lori Schneider of the US State of Wisconsin has become what is believed to be the first person with diagnosed multiple sclerosis to get to the top of Mt Everest. Lori Schneider, aged 52, reached the top of the world in the early hours of Saturday morning London time, carrying with her a banner celebrating the upcoming World MS (Multiple Sclerosis) Day on Wednesday 27 May (http://www.worldmsday.org). The banner reads: "Join the Global Movement. End MS!" (Note to picture editors: photo will be available as soon as Lori Schneider descends).
The Health and Safety Executive (HSE) is to prosecute Sellafield Ltd for alleged breaches of health and safety law. This follows HSE"s investigation into the exposure of two contractor employees to airborne radioactive contamination on 11 July 2007 at Sellafield Nuclear Licensed Site in Cumbria.
A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), components of the National Institutes of Health, supported the study, which appears in the May/June issue of Child Development.
The recent H1N1 influenza epidemic has raised many questions about how animal viruses move to human populations. One potential route is through veterinarians, who, according to a new report by University of Iowa College of Public Health researchers, are at markedly increased risk of infection with zoonotic pathogens -- the viruses and bacteria that can infect both animals and humans.
If the heart muscle does not have enough blood (and consequently oxygen) it dies and a heart attack occurs. Another name for a heart attack is myocardial infarction, cardiac infarction and coronary thrombosis. According to Medilexicon"s medical dictionary, a heart attack is "infarction of a segment of heart muscle, usually due to occlusion of a coronary artery". (Infarction = the process whereby an area of dead tissue is caused by a loss of blood supply).
The 22nd Congress of the European College of Neuropsychopharmacology (ECNP) will be held from 12-16 September 2009 in Istanbul, Turkey.
Stem cells that respond after a severe injury in the lungs of mice may be a of rapidly dividing cells that lead to lung cancer, according to a team of American and British researchers.
On May 27 and 28, 2009, the Food and Drug Administration (FDA) will hear testimony about the FDA-guided effort to develop a classwide Risk Evaluation and Mitigation Strategy (REMS) for all controlled-release opioids from more than 70 patients, scientists, public health professionals, and representatives of pharmacist groups, prescriber groups, and pharmaceutical companies. Controlled-release opioids include prescription pain medications that release the medication over a period of several hours and contain fentanyl, hydromorphone, methadone, morphine, oxycodone, or oxymorphone. More than 21 million prescriptions are written every year for these medications.
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced that the efficacy portion of its first Phase 3 clinical trial evaluating its novel LEVADEX(TM) orally inhaled migraine therapy met all four primary endpoints. Additional endpoints showed that LEVADEX provided rapid and sustained pain relief for up to 48 hours after dosing.
United Therapeutics Corporation (Nasdaq: UTHR) announced that the United States Food and Drug Administration (FDA) has approved ADCIRCA(TM) (tadalafil) tablets for oral administration, with a recommended dose of 40 mg, as the first once-daily phosphodiesterase type 5 (PDE5) inhibitor for the treatment of pulmonary arterial hypertension (PAH). ADCIRCA is indicated to improve exercise ability in WHO Group I PAH patients, which encompasses patients with multiple forms of PAH including etiologies such as idiopathic and familial PAH as well as PAH associated with scleroderma and congenital heart disease.
Penicillin and other antibiotics in the beta-lactam family work as well as other antibiotics to treat MRSA (methicillin-resistant Staphylococcuss aureus) infections in the skin and soft-tissue of children and may help prevent further resistance to antibiotic treatment, according to a new study funded by the Agency for Healthcare Research and Quality.
Better science, better regulation and better access policies are needed in Europe to support an
Columbia University Science & Technology Ventures (STV) and New York-based EndoRobotics, Inc. have entered into an exclusive license agreement to develop and commercialize a micro-robotic imaging and surgical device platform designed to reduce the complexity of minimally invasive surgical (MIS) procedures and improve patient outcomes.
California (USC) have identified a
President Obama this morning announced Judge Sonia Sotomayor of the Second Circuit Court of Appeals as his nominee to replace retiring Supreme Court Justice David Souter, the New York Times" "The Caucus" reports. Sotomayor, if confirmed, would be the first Hispanic to serve on the court and, with Justice Ruth Bader Ginsburg, bring the number of female justices currently on the court to two. White House officials said the president made his decision over the Memorial Day weekend after narrowing his list of candidates to four. s close to the selection process said the other candidates included Federal Appeals Judge Diane Wood, Homeland Security Secretary Janet Napolitano and Solicitor General Elena Kagan (Zeleny, "The Caucus," New York Times, 5/26). According to the Washington Post, Obama has set a deadline of having Sotomayor confirmed before the Senate"s five-week recess that begins Aug. 7 (Shear et al., Washington Post, 5/26). Sotomayor, a graduate of Princeton University and Yale Law School, joined the federal district court in 1992 after being nominated by former President George H.W. Bush. Former President Clinton nominated her to the appeals court in 1997, and she was confirmed in 1998 (Baker/Zeleny, New York Times, 5/26). The Post reports that many analysts considered Sotomayor a likely pick to replace Souter, who announced his retirement earlier this month (Washington Post, 5/26). According to the Times, Sotomayor"s past statements that her ethnicity and gender are important factors in serving as a judge "could generate debate" during the nomination process. In a 2002 lecture, Sotomayor said, "I would hope that a wise Latina woman with the richness of her experiences would more often than not reach a better conclusion than a white male who hasn"t lived that life" (New York Times, 5/26). Both liberal and conservative advocates were quick to release statements on the selection after the announcement this morning. Doug Kendall, president of the liberal Constitution Accountability Center, said, "We already know that she is a brilliant lawyer who is committed to ruling based on the Constitution and the law, not on her own personal political views." Wendy Long, counsel to the conservative Judicial Confirmation Network, said in an e-mail to reporters that Sotomayor "is a liberal judicial activist of the first order who thinks her own personal political agenda is more important than the law as written. She thinks that judges should dictate policy, and that one"s sex, race and ethnicity ought to affect the decisions one renders from the bench" (Washington Post, 5/26). According to Politico, of the nominees Obama was considering, Sotomayor was the one that Republicans indicated "they would complain most loudly about." However, the Democratic control of the Senate makes it unlikely that Republicans could block her confirmation, Politico reports (Allen/Martin, Politico, 5/26). Over the weekend, Senate Minority Whip Jon Kyl (R-Ariz.), a member of the Senate Judiciary Committee, said that senators from both parties "reserve the right to not only oppose a nomination, but also prevent the vote on a nomination" (Wilson, The Hill, 5/25). Kyl also said that although the GOP likely does not have enough votes for a filibuster, he would attempt to delay the nomination if Obama chose someone outside what he considers the mainstream. He said, "We will distinguish between a liberal judge on one side and one who doesn"t decide cases on the merits but, rather, on the basis of his or her preconceived ideas" (Washington Times, 5/25). Obama Discusses Nomination in C-SPAN InterviewIn an interview on Friday with C-SPAN, Obama said he would like to choose a Supreme Court justice who has "a little bit of a common touch" and a "practical sense of how the world works," the Post reports. Obama added that he "continue[s] to believe" that "empathy" is an important quality in a justice, despite Republican criticism that his emphasis on the quality means that he seeks a judge with an "activist" agenda, the Post reports
Cancer patients treated with the widely used drug bevacizumab in combination with chemotherapy are at significantly greater risk of potentially life-threatening gastrointestinal (GI) perforations (a hole in the wall of the stomach, small intestine or large bowel)-particularly patients with advanced colorectal cancer and renal cell cancer, according to an Article published Online First and in the June edition of The Lancet Oncology.
The AMA says the most alarming element of last night"s budget is the total absence of health support measures for the unemployed.
Preliminary results from a double-blind, randomised, multicentre trial among 660 patients with chronic obstructive pulmonary disease (COPD) show that budesonide/formoterol (Symbicort®: AstraZeneca) plus tiotropium (Spiriva™: Boehringer Ingelheim Limited) significantly improves disease control and patients" quality of life.1,2
Health officials recently held a regional consultation in Kenya to examine mother-to-child HIV transmission services and pediatric HIV/AIDS care in nine Eastern and Southern African countries, IRIN/PlusNews reports. The consultation -- hosted by UNICEF, UNAIDS and the World Health Organization -- included representatives from Ethiopia, Kenya, Malawi, Mozambique, South Africa, Swaziland, Tanzania, Uganda and Zambia. The meeting addressed issues in MTCT prevention services -- including the continued use of single-dose nevirapine instead of more effective combination therapies, as well as delays in diagnosing and initiating treatment -- that are weakening prevention programs in focus countries. According to IRIN/PlusNews, 70% of pregnant women in Eastern and Southern African countries are seen by a health care provider at least once during pregnancy. However, 43% of HIV-positive pregnant women have a health care worker present during labor who can administer PMTCT treatment. In Uganda, a national policy calls for all sub-county level health facilities to provide PMTCT services, but only 53% offer such services because of health worker shortages. Janet Kayita, regional PMTCT adviser for UNICEF, said, "We are doing a bad job of testing women for HIV and then following them up, and an even worse job of ensuring that infants receive appropriate prevention and treatment services." She added that national PMTCT guidelines have not reached local levels. "These policies must become a reality for the people they were designed to help," Kayita said, adding that primary health care systems at all levels must be strengthened (IRIN/PlusNews, 5/25).Some officials at the meeting called on African governments to reach 80% of pregnant women, mothers and children with services; reduce by 50% the number of women and infants who do not receive follow-up care; and double the number of HIV-positive children who receive antiretroviral treatment. Xinhuanet reports that prevention services currently reach about 50% of pregnant women in all Eastern and Southern African countries. At the close of the consultation, officials issued a set of recommendations for meeting PMTCT goals, including increased community involvement in prevention programs; reduced workloads for health workers; and increased coverage of and compliance with PMTCT regimens. In addition, the experts urged governments to prioritize regions with high HIV burdens and strengthen data management to better understand trends (Ooko, Xinhuanet, 5/25). James Kamau, coordinator of the Kenya Treatment Access Movement, recommended that more women in the country deliver in hospitals in order to ensure that they receive PMTCT services (Mwaniki, Daily Nation, 5/25). David Alnwick, a UNICEF regional adviser, said, "It is critical at this juncture, when many countries are faced with shrinking budgets and competing demands, that we do not lose the momentum of what needs to be done to create an AIDS-free generation" (Xinhuanet, 5/25).
U.S. Senator Mel Martinez (R-FL) introduced an effort aimed at updating the U.S. Census" current function questions to better improve our nation"s long-term care services and support systems. By replacing a small portion of the survey with standardized function questions used by medical providers, the Disability Data Modernization Act will provide more accurately collected data used for planning the future health care needs of elderly and disabled Americans.
A new study has found that some black women with advanced breast cancer declined treatment with chemotherapy or radiation, though researchers did not know the reason why so many of the women opted against treatment, HealthDay/Las Vegas NOW reports. For the study, researchers examined records for 107 women with cases of advanced breast cancer that were reported at one inner-city hospital between 2000 and 2006. Eighty-seven percent of the women were black, and 29% of them had breast cancer tumors that did not respond well to new, targeted treatments. Of all women, 20.5% declined chemotherapy and 26.3% opted against radiation.Lead researcher Monica Rizzo, an assistant professor of surgery at the Division of Surgical Oncology at the Emory University School of Medicine, said the reason why the women declined treatment is not clear, adding, "We looked at marital status, as well as religious background, of those women, and unfortunately, we were not able to find any clear identifier." Researchers speculated that fear of the medical system, poverty and cultural differences might play a role. Rizzo"s group has started a community outreach program through which a nurse practitioner and social worker follow up with breast cancer patients (Reinberg, HealthDay/Las Vegas NOW, 5/22). An abstract of the study is available online.
A REVIEW OF THE HHS FAMILY PLANNING PROGRAM: MISSION, MANAGEMENT, AND MEASUREMENT OF RESULTS, new from the Institute of Medicine, recommends that family planning be re-established as a core value in public health practice. The report urges the Department of Health and Human Services and Congress to support the Title X program as the leading voice for the nation"s family planning effort.
Almost 40% of U.S. births in 2007 occurred among unmarried women, according to a report from the Centers for Disease Control and Prevention"s National Center for Health Statistics, the Washington Post reports. About 1.7 million infants were born to unmarried women in 2007, representing a 26% increase over the 1.4 million in 2002 and more than double the number in 1980. Unmarried women accounted for 39.7% of all U.S. births in 2007, up from 34% in 2002 and more than double the percentage in 1980, according to the report, which studied birth certificates nationwide.Women in their 20s and 30s are the biggest drivers of the trend, with out-of-wedlock births in this age group increasing from a rate of 13% to 34% between 2002 and 2006, according to the report (Stein/St. George, Washington Post, 5/14). For example, the birthrate for unmarried women ages 30 to 34 rose by 34% in 2007 compared with 2002 (Harris, New York Times, 5/14). Sixty percent of births to women ages 20 to 24 were to unmarried women, compared to 52% in 2002. In addition, 32% of births to women 25 to 29 were to unmarried women, compared to 25% in 2002, the report shows (Jayson, USA Today, 5/14). Overall, women in their 20s made up 60% of U.S. unmarried births in 2007, while teens accounted for 23% and women ages 30 and older accounted for 17% (New York Times, 5/13). Unmarried Hispanic women gave birth at a rate of 106 births per 1,000 unmarried women. The rate was 72 per 1,000 for blacks, 32 per 1,000 for whites and 26 per 1,000 for Asians. The rates for blacks and Hispanics rose the fastest, according to the report (Washington Post, 5/14). Compared with other countries, the U.S. rate of unmarried births was near the middle of the 14 countries included in the report (USA Today, 5/14).Although researchers did research the reasons for the trend, they cited several factors that in combination likely affected the rate, including a decrease in the social stigma surrounding out-of-wedlock births, an increasing number of couples putting off or forgoing marriage, and growing numbers of financially independent, older or single women who choose to have children on their own (Washington Post, 5/14). Researchers noted that most of the increase in these births was among parents who live together but are not married (New York Times, 5/13)."I think this is the tipping point," Rosanna Hertz of Wellesley College said, adding, "This is becoming increasingly the norm. The old adage that "first comes love, then comes marriage, then comes baby in the baby carriage" just no longer holds true." Hertz added, "Women can have children on their own, and it"s not going to destroy your employment, and it"s not going to mean that you"ll be made a pariah by the community. It"s much more socially acceptable." Sarah Brown of the National Campaign To Prevent Teen and Unplanned Pregnancy said, "I look at this and say, maybe this trend is what young adults want or stumble into, but it"s not in the best interest of children" (Washington Post, 5/14).
UCB today announced that Vimpat® (lacosamide) C-V, a new antiepileptic drug (AED) is available in the U.S. as an add-on therapy for the treatment of partial-onset seizures in people with epilepsy who are 17 years and older. Vimpat® will be available in U.S. pharmacies by the first week of June 2009.
Targeted Molecular Diagnostics (TMD), a Quintiles Central Laboratory, announced the availability of two new laboratory tests used to develop more effective cancer treatments.
New findings by researchers UT Southwestern Medical Center are accelerating efforts to eradicate worm infections that afflict a third of the world"s population.
Aphios Corporation announced that the results of a Phase II/III clinical trial of Zindol® for cancer chemotherapy induced nausea will be presented at the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO) being held from May 29 to June 02, 2009 in Orlando, FL. Zindol® is an enhanced ginger product.
Even though a significant improvement is evident in the care of patients with diabetes over the last ten years, they are not considered as a direct result of the quality and outcomes framework, considered as the method that rewards UK general practices to ensure quality care.
UNICEF has appealed for an additional $41.4 million to provide urgent assistance to people displaced by fighting in northwest Pakistan. Over half of the displaced are children. UNICEF Pakistan has now almost exhausted its contingency stocks of supplies and funding.
Crohn"s disease is an ongoing condition that causes inflammation of the digestive tract, or the GI (gastrointestinal) tract (the gut). Crohn"s disease may also be called ileitis or enteritis. Crohn"s disease can affect any part of the gut, from the mouth all the way down to the anus. In the majority of cases the lower part of the small intestine - the ileum - is affected. Patients with Crohn"s disease can feel pain; the condition makes the intestines empty frequently, resulting in diarrhea.
A research team led by a University of Iowa investigator has generated DNA-like compounds that effectively inhibit the cells responsible for systemic lupus erythematosus -- the most common and serious form of lupus. There currently is no cure for this chronic autoimmune condition that damages the skin, joints and internal organs and affects an estimated one million Americans.
Cedars-Sinai Medical Center"s Gynecologic Oncology Division was named among the nation"s top 10 programs by Contemporary OB/GYN, a leading publication read by the nation"s obstetricians and gynecologists.
A new study found that compared with two decades ago, fewer Americans are following a healthy lifestyle. This is despite the mounting evidence
Merrill Egorin, M.D., professor of medicine and pharmacology at the University of Pittsburgh Cancer Institute (UPCI), has received the 2009 American Society of Clinical Oncology (ASCO) Translational Research Professorship for his work in improving cancer treatments and supporting the next generation of researchers.
Nearly 1,200 community health centers nationwide have received a boost of funding from the federal economic stimulus package, which is helping some of the facilities that were on the verge of closing remain open and continue treating low-income and uninsured patients, PBS" "NewsHour with Jim Lehrer" reports. More people are seeking care at such facilities as they lose their jobs and employer-sponsored health insurance as a result of the economic recession. At the same time, funding for the centers has dropped because of cutbacks in state and local funding and lower not-for-profit donations and grants. The stimulus package provides a total of $20 billion for clinics to maintain and increase services. "NewsHour" profiles community health centers in Lorain, Ohio, which likely would have closed without the additional funds from the economic stimulus package (Bowser, "NewsHour with Jim Lehrer," PBS, 5/26).
Authorities in South Africa have begun construction of one of the 20 planned Football for Hope centers in Africa -- part of a 2010 World Cup campaign called "20 Centers for 2010" aimed at reducing the prevalence of HIV/AIDS, poverty and crime in local communities -- the AP/Google.com reports. The center under construction in South Africa"s Khayelitsha township will include a soccer field, community center and after-school programs that will focus on sex education and HIV/AIDS education. The International Federation of Football Association, or FIFA, in alliance with Streetfootballworld, a network of development groups, is providing the campaign with $10 million in funding. Ghana, Kenya, Mali, Namibia, Rwanda and other African countries will be home to the remaining 19 centers.According to FIFA President Joseph Blatter, the campaign "emphasizes the power of football far beyond the boundaries of the pitch." He added that the centers will "provide a platform for communities to address social issues such as children"s rights, education, health, HIV/AIDS prevention and will leave a legacy for Africa that will last long after the final whistle of the 2010 FIFA World Cup has been blown." Helen Zille, premier of the Western Cape Province, said construction of the center in the township "shows what we can do when we focus on getting things right rather than concentrating on what"s wrong," adding that she hopes the center is successful with its HIV/AIDS education efforts. The center will be run by Grassroots Soccer, an HIV/AIDS education organization that uses the sport to educate youth. Nocawe Tyali, a life-skills and football teacher who works with teenagers, said the new center will give young people an alternative to high-risk behaviors and enable the area to offer more youth football programs that include an HIV/AIDS prevention message (Nullis, AP/Google.com, 5/25).
When American patients trust their health to a for-profit insurance company, they"re doing nothing less than gambling with their lives. Registered nurses from the National Nurses Organizing Committee and California Nurses Association today announce the launch of a new healthcare video game, based on this idea, called "You Bet Your Health." The game is part of a wide-ranging public education and political mobilization campaign for single-payer health reforms, which is the choice of nurses and doctors. The game can be viewed at http://www.YouBetYourHealth.com
For thousands of years ginger has been treasured for its reputed health benefits, in particular for treating digestive problems including nausea.
Agendia, a world leader in molecular cancer diagnostics,
Variations in both milk feeding and in the weaning diet are linked to differences in growth and development, and they have independent influences on body composition in early childhood, according to a new study accepted for publication in The Endocrine Society"s Journal of Clinical Endocrinology & Metabolism (JCEM).
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced that the efficacy portion of its first Phase 3 clinical trial evaluating its novel LEVADEX™ orally inhaled migraine therapy met all four primary endpoints. Additional endpoints showed that LEVADEX provided rapid and sustained pain relief for up to 48 hours after dosing.