Diagnostics
Australia"s general practices stand ready to work with Government to begin vaccinating vulnerable Australians against HINI (Swine Flu) as soon as a vaccine becomes available, the AMA said today.
A study to be published in the August 2009 edition of Applied Cognitive Psychology sheds new light on how Cogmed Working Memory Training and stimulant medication address working memory impairments in children with ADHD. Working memory, acknowledged as one of the core deficits in ADHD, represents the brain"s ability to hold and process critical information related to the present moment. This study represents the latest findings from a team of independent UK researchers whose ongoing work examines the impact of Cogmed"s software-based training program on individuals with disorders of memory and attention.
The U.S. will work to address the health challenges facing India among other countries and will aim to improve maternal and child health care services through comprehensive dialogue, Secretary of State Hillary Clinton said on Friday after visiting a Self Employed Women"s Association (SEWA) trade outlet in Mumbai, India, PTI/Yahoo! News reports. Clinton said, "Our government is already spending a lot of money on HIV/AIDS but we wanted to add maternal and child health to that commitment as it is important for India." She added that the funding will be used to combat tuberculosis and polio, "which are also problems in India" (7/18).
Visitors at next week"s Royal Bath and West Show will have the opportunity to find out what jobs and training schemes are on offer at Yeovil District Hospital.
The individual health insurance market is not a viable option for the majority of uninsured adults, a new report from The Commonwealth Fund finds. Seventy-three percent of people who tried to buy insurance on their own in the last three years did not purchase a policy, primarily because premiums were too high. In addition, among adults with individual coverage or who tried to buy coverage in the past three years, 57 percent said it was very difficult or impossible to find coverage they could afford, 47 percent said it was very difficult or impossible to find a plan with the coverage they needed, and 36 percent were denied coverage or charged more because of a pre-existing condition, or had the condition excluded from their coverage.
Young men who stay at home with their parents are more violent than those who live independently, according to new research at Queen Mary, University of London.
Charles Nichols, PhD, Assistant Professor of Pharmacology at LSU Health Sciences Center New Orleans, has been awarded a grant in the amount of $1.4 million over four years by the National Institutes of Health"s National Institute of Mental Health to find and characterize novel genes involved in psychosis and schizophrenia, using novel research methods.
The former Ghanaian president, John Kofi Agyekum Kufuor, has
Stagnation in HIV/AIDS funding and the high cost of new medicines are putting the lives of thousands of poor patients at risk, the international medical humanitarian organization Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF) warned today at the 2009 International AIDS Society conference in South Africa . Patients needing new drug regimens will return to AIDS "death row." While the lack of access to antiretroviral treatment for seven million people remains unaddressed, inadequate financing now further threatens treatment scale-up.
The World Health Organization (WHO) said earlier today, Tuesday, that countries should consider closing schools as a way to slow the spread of
Provectus Pharmaceuticals, Inc. (OTC BB: PVCT ), a development-stage oncology and dermatology biopharmaceutical company, has initiated a new Phase 2 clinical trial of PH-10 for psoriasis involving daily dosing of patients for 28 days. After reviewing safety and efficacy data from its PH-10 trial for atopic dermatitis, Provectus determined that daily dosing of patients with psoriasis trial would be an appropriate and attractive regimen. The new study supplants an earlier Phase 2 study, using twice weekly dosing for 12 weeks, which was terminated earlier in June.
CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, announced that treatment with its cancer drug candidate INNO-206 resulted in a statistically significant reduction in the average primary tumor size in an animal model of pancreatic cancer, outperforming the broadly used chemotherapeutic drug doxorubicin, as well as the current standard of care in pancreatic cancer treatment, gemcitabine.
The president of the California Medical Association, Dev A. GnanaDev, issued the following statement today in regards to the announced state budget deal:
The American Dental Hygienists" Association (ADHA) recently awarded Minnesota State Senator Ann Lynch with a presidential citation to recognize her extraordinary efforts in passing legislation which will establish new oral health providers in Minnesota.
"President Obama is becoming more personally invested in rallying the public and Congress behind a healthcare overhaul, even as some Republicans raise the stakes in the debate by claiming that defeating his plan would undermine his presidency," the Los Angeles Times reports. Obama will defend his push for health reform in a series of public events this week, as he and senior aides press Democratic lawmakers to support the versions of pending legislation still circulating in congressional committees (Parsons and Levey, 7/21).
Health companies and their employees gave Sen. Max Baucus, D-Mont., nearly $1.5 million in 2007 and 2008, just as the Senator was readying the Senate Finance Committee to consider health reform, The Washington Post reports.
"The ad wars over the health care campaign are heating up once [again] this week," The New York Times reports. At a speech on Monday, Michael Steele, chairman of the Republican National Committee, released a party television ad "which its spokeswoman says will first be broadcast in Arkansas, North Dakota and Nevada." The ad "opens with a tiny infant, and spools out with a narrator"s voice saying: "They"ve loaned Barack Obama their future, without even knowing it. Trillions for rushed government bailouts and takeovers, banks, the auto industry." And then it continues, as children appear on the screen: "The biggest spending spree in our nation"s in history. And they"ll have to pay. The next big ticket item? A risky experiment with our health care. Barack Obama"s massive spending experiment hasn"t healed our economy. His new experiment risks their future and our health.""
Timeframe before conception may be linked to disease later in life
The Department of Health announced there would be an independent investigation into Mid Staffordshire NHS Foundation Trust and has proposed changes to legislation governing Foundation Trusts.
Health and Human Services Secretary Kathleen Sebelius released new data from the Nationwide Emergency Department Sample - the largest, all-payer emergency department database in the United States. The Nationwide Emergency Department Sample is designed to help public health experts, policymakers, health care administrators, researchers, journalists and others find the data they need to answer questions about care that occurs in U.S. hospital emergency departments.
Broncus Technologies, Inc., a medical device company focused on developing minimally-invasive innovations for lung diseases, announced today at the International Conference of the American Thoracic Society (ATS) the release of its first commercial products: the LungPoint™ Virtual Bronchoscopic Navigation and Treatment Planning System, Yield™ Mini Doppler Probe, and Yield™ Transbronchial Coring Needles. These devices are for use in interventional bronchoscopic procedures for lung cancer and other diseases.
The National Institute for Health and Clinical Excellence (NICE) today issued its recommendation for the use of MabThera® (rituximab) in the UK"s most common form of leukaemia, chronic lymphocytic leukaemia (CLL).1,2,3 NICE"s final guidance recommends rituximab in combination with fludarabine and cyclophosphamide (FC) chemotherapy as an option for previously untreated patients with CLL.4 The addition of rituximab to FC chemotherapy has been proven to halt progression of the disease by 10.5 months longer than chemotherapy alone, and more than doubles the number of CLL patients achieving complete remission, compared to chemotherapy.5,6 More than 20,000 people in the UK are living with CLL and there are an estimated 3,700 new cases every year.7,8 Professor John Gribben, Consultant Haematologist and Medical Oncologist, Barts and The London NHS Trust, commented:
Taking eye drops multiple times a day can be difficult for patients to do, and because of blinking and tearing, as little as 1 to 7 percent of the dose is actually absorbed by the eye. Now, researchers led by Daniel Kohane, MD, PhD, director of the Laboratory for Biomaterials and Drug Delivery at Children"s Hospital Boston, have developed special contact lenses that can gradually dispense a constant amount of medication to the eye, at adjustable rates. They describe their prototype lens in the July issue of Investigative Ophthalmology and Visual Science.
Foresight Biotherapeutics, Inc. announced completion of a multi-center open-label pilot study of FST100 in the treatment of viral conjunctivitis. FST-100 is a novel formulation of dexamethasone that includes povidone iodine. The trial studied patients with clinical signs and symptoms of acute conjunctivitis who tested positive for adenoviral antigen by the RPS Adeno Detector® (RPS). Patients were enrolled in a single arm utilizing FST-100 topical ophthalmic suspension given 4 times daily for 5 days. The RPS Adeno Detector® test was performed at baseline and at each visit along with conjunctival swabs for adenoviral titers by quantitative PCR (qPCR) and cell culture with confirmatory immunoflourescence (CC-IFA). The primary endpoint of the study was clinical resolution of conjunctival injection and conjunctival discharge. These signs were scored on a scale from zero to three. Secondary endpoints included reduction of viral titers measured by qPCR and eradication of infectious virus determined by CC-IFA.
Gilead Sciences, Inc. (Nasdaq:GILD) highlighted results from a study known as DART (Development of Anti-Retroviral Treatment in Africa), which evaluated the need for routine laboratory monitoring in adults taking antiretroviral therapy in Africa. The DART trial was an open-label, randomized study comparing clinical and laboratory monitoring to clinical monitoring alone for efficacy and toxicity. In this study, 74 percent of patients were on a treatment regimen containing Viread® (tenofovir disoproxil fumarate). At baseline, more than 50 percent of patients had reduced renal function. The results indicated that Viread was well tolerated and that the incidence of renal adverse events was low. DART researchers concluded that renal function test results were similar in both arms of the trial for up to five years, suggesting that routine monitoring of Viread may not be necessary in re-limited settings when using the product as part of a first-line HIV treatment regimen. The results of the study were presented today at the 5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2009) in Cape Town, South Africa.
W. L. Gore & Associates (Gore) today announced that it has received approval from the US Food and Drug Administration (FDA) to market the most up-to-date design for the GORE VIABAHN® Endoprosthesis for device diameters 9 - 13 mm. The next generation of the large diameter product enables streamlined deployment on the same 0.035" guidewire and TIP to HUB direction as the 5 - 8 mm sizes. Additional modifications to the large diameter GORE VIABAHN Endoprosthesis include radial device expansion, a contoured proximal edge and a lower profile that is now available for most sizes.
Scientists at the University of Tennessee, Knoxville, and Lawrence Berkeley National Laboratory (LBNL) have published new findings about a cause of a condition at the root of genetic disorders such as Down Syndrome, pregnancy loss and infertility.
Research conducted in New York City found that children exposed to urban air pollution before birth were more likely to have a lower IQ than
Purdue University researchers have created magnetically responsive gold nanostars that may offer a new approach to biomedical imaging.
The Committee for a Responsible Federal Budget released "Health Care and the Federal Budget," documenting the alarming state of the U.S. health care system with a special focus on the role of health care in the federal budget.
Men who exercised regularly, drank moderately, did not smoke, who were not overweight and had a diet that included cereal and fruits and vegetables had a lower lifetime risk of heart failure, according to a study in the July 22/29 issue of JAMA.
Novavax, Inc. (Nasdaq: NVAX) announced final selection of a Respiratory Syncytial Virus (RSV) vaccine candidate that will be advanced into additional preclinical studies to support an Investigational New Drug (IND) application. As previously announced, Novavax has been evaluating a number of RSV vaccine candidates, all of which have successfully induced antibody responses in mice. Novavax scientists have now engineered a new vaccine candidate which has been shown to protect mice against RSV disease and can be produced at sufficient yields to allow commercial manufacture. This new candidate is directed against a protein on the surface of the virus, the "F" or "fusion" protein, which is the protein that the virus uses to infect and fuse with cells in the respiratory tract and cause disease.
Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.
For years, George Forschler knew the mitral valve in his heart was failing and would eventually need repair or replacement. Concerned about the risks associated with open heart surgery the traditional way to access a mitral valve he did his best to postpone the inevitable. Forschler, a retired U.S. Air Force Brigadier General who now heads a consulting firm, kept his heart healthy by exercising at the gym and doing weekend chores on his farm near here.
The California Medical Association today praised the state Department of Insurance (DOI) for conducting a public hearing this week on its proposed regulations to prevent private insurers from unjustly canceling health coverage for patients after they get sick and file an expensive claim. The DOI released the proposed regulations last month.
An exploratory study to be published in BJOG: An International Journal of Obstetrics and Gynaecology, has shown that women going into early preterm labour (before 34 weeks gestation) have low-levels of progesterone in their saliva as early as 24 weeks, and that moreover, these levels fail to rise during pregnancy in the normal way. This offers the possibility of developing a simple, non-invasive test to identify women at increased risk of delivering early.
Five centrist House Democrats, led by antiabortion-rights Rep. Tim Ryan (Ohio), on Tuesday issued a proposal that would neither require nor ban private insurers from covering abortion services as long as federal dollars are not used, the Washington Post"s "Capitol Briefing" reports. In a letter sent to House Speaker Nancy Pelosi (D-Calif.), Ryan and Reps. Dale Kildee (Mich.), James Langevin (R.I.), Artur Davis (Ala.) and Kendrick Meek (Fla.) said that their proposal "maintains the current status quo in the private market" and would not "preempt constitutionally permissible" state restrictions related to abortion, such as parental notification laws. The representatives called their proposal a "common ground solution." Current federal law prohibits the use of federal Medicaid funds for abortion services in nearly all circumstances. The lawmakers said that they are "increasingly concerned about potential roadblocks around the issue of abortion" in the health reform debate in Congress. According to "Capitol Briefing," antiabortion-rights Democrats are concerned that health reform legislation could lead to indirect federal funding of abortion services through private insurers participating in a proposed health insurance exchange (Eggen, "Capitol Briefing," Washington Post, 7/21). In the letter, the representatives said that they would like to include language in the final health reform bill "that makes clear that no insurance company will be required to pay for an abortion except in extraordinary circumstances." In addition, insurance providers would not be prohibited from paying for abortion services "so long as health insurance plans offered in the exchange that choose to provide abortion coverage pay for those services with funds that are separate and distinct from any federal subsidies," the letter said. Ryan said he hopes the proposal will be introduced in committee on Wednesday as an amendment (Smith, Politico, 7/21).House Members Step Up Efforts To Exclude Abortion CoverageMeanwhile, antiabortion-rights House members are intensifying their efforts to exclude abortion coverage from the chamber"s health reform bill (HR 3200), which they said includes a "hidden mandate" that would allow federal money to cover the procedure, the AP/Houston Chronicle reports. Rep. Bart Stupak (D-Mich.) said that he plans to join other antiabortion-rights House members at a news conference on Wednesday to criticize the legislation. Stupak helped draft a June 25 letter to Pelosi saying that he and 19 other Democrats would not support any health reform bill "unless it explicitly excludes abortion from the scope of any government-defined or subsidized health insurance plan." The bill does not mention abortion, which supporters say means that the legislation is neutral on the issue (Alonso-Zaldivar, AP/Houston Chronicle, 7/22).Antiabortion-Rights Coalition Launches CampaignA coalition of antiabortion-rights groups this week is launching a three-week campaign aimed at excluding abortion coverage from health reform legislation, Politico reports. The coalition includes James Dobson, founder of Focus on the Family; Tony Perkins, president of the Family Research Council; Richard Land of the Southern Baptist Convention; David Bereit of 40 Days for Life; and Charmaine Yoest, president of Americans United for Life. Yoest said AUL intends to send a letter to President Obama on Thursday citing its "belief that the bills are intended to include abortion."Laurie Rubiner, vice president for public policy and advocacy at the Planned Parenthood Federation of America, said that abortion is "not mandated any more than any other service or procedure in health reform." She added that excluding abortion coverage could result in women losing the coverage they currently have under private plans. The abortion-rights opponents" demand to exclude abortion coverage "violates the first principle of health care reform, which is: Don"t make people worse off under health care reform than they are today," Rubiner said (Smith, Politico, 7/22).
The medical, legal and interpersonal processes involved with a surrogate birth have changed significantly since the controversial "Baby M" case two decades ago, the New York Times reports. In the case, the surrogate was the infant"s biological mother and unsuccessfully sought custody of the child after birth. The Times reports that the legal proceedings in the case helped reinforce the validity of surrogacy contracts, which are now standard practice.Most couples today use a gestational surrogate -- meaning that they have no genetic link to the woman carrying the fetus -- and some choose to maintain friendships with the surrogate after birth. According to the Times, people might choose gestational surrogacy if the woman lacks a uterus, has a malformed uterus, must take medication incompatible with pregnancy, or has had repeated miscarriages or failures at in vitro pregnancies. Male couples or single men might also use this option.Legal protections have strengthened since the Baby M case, although surrogacy remains illegal in some states. State laws also vary in the steps required to ensure that the parents" names, rather than the surrogate"s, are on the child"s birth certificate.Despite an increase in popularity, surrogacy remains "fraught with controversy" over criticisms that compensation to surrogates amounts to "baby selling" and exploitation of low-income women, according to the Times. However, surrogacy advocates say that most women who choose to become surrogates have altruistic motives. Surrogates typically receive between $15,000 and $20,000 as compensation for carrying the pregnancy and undergoing hormonal preparations. The Times reports that reputable agencies and lawyers who specialize in surrogacy help guard against exploitation and spurious motives for seeking a surrogate pregnancy. Prospective surrogates and parents typically undergo psychological screening and legal guidance, and most lawyers require that surrogates meet certain age and health criteria (Brody, New York Times, 7/21).
President Barack Obama prepares his primetime address for tonight as he ups the ante for reform. This week alone, Obama has visited two hospitals, made a trip to Cleveland for a town-hall meeting and conducted a conference call urging bloggers to motivate their followers. Such efforts come amid increasing difficulties and roadblocks set by the GOP as health care bills stall in Congress.
"Many small businesses are worried that rising health insurance costs are choking their growth and hindering the creation of new companies, and they fear health care reform plans being debated in Congress and by the Obama administration could end up costing them even more in taxes, according to business advocates," the Baltimore Sun reports. Some of those views were collected in a survey released Tuesday by the U.S. Public Interest Research Group. According to the survey 29 percent of [309] businesses were unable to offer insurance to their employees, and many said their health care costs had risen this year. "Rising health care costs are choking American small businesses just when we need them the most," said Nicholas Green, an organizer for the research group"s Maryland contingent (Sentementes, 7/22).
Young adults are facing tough times with limited job prospects and no health insurance. The Associated Press reports on recent college graduate Emily Weinstein as being representative of the many young uninsured Americans: "Like millions of other uninsured adults in their 20s, Weinstein is watching Congress as it advances legislation to overhaul health care. The recession has deepened young adults" career struggles. It has also sharpened their interest in health insurance. Already the least likely of any age group to have coverage, adults in their 20s face brutal job searches and more time uninsured because of the recession. Nearly 30 percent, 13.2 million, were uninsured in 2007, according to the Commonwealth Fund, a New York-based research center. Many young adults work entry-level jobs without insurance and, despite new laws in some states, they"re eventually too old to stay on their parents" policies."
A proposal in Massachusetts to end the practice of paying doctors for individual procedures could prove a model to hold down costs for U.S. health care reform, Reuters reports.
Eleven Baltimore churches on Tuesday provided HIV testing to local residents as part of a larger effort by the JACQUES Initiative, a program at the University of Maryland School of Medicine"s Institute of Human Virology, the Baltimore Sun reports. The JACQUES Initiative launched Project SHALEM in partnership with the Maryland AIDS Administration and several local faith-based and community organizations, according to the Sun. Derek Spencer, the executive director of the JACQUES Initiative, said, "The ultimate goal is to make churches, mosques and synagogues a safe place where people can receive HIV support. We are no longer going to wait for people to come into our academic centers for help." He said organizers hoped to test 1,000 people, noting that at one of the testing sites, within the first hour, four people tested positive with the rapid oral swab tests. Angela Wakhweya, deputy director of the Maryland AIDS Administration, said the goal of the project is to eliminate new HIV cases in the state (Bass, 7/22).
Stokes caused by non-traumatic intracerebral haemorrhage (IH) are caused by a rupture of blood vessels in the brain. This is a major public health problem which accounts for 2 million (10-15%) of a total of 15 million strokes worldwide each year. The causes and the future treatment of this condition are discussed in a Seminar in this week"s edition of The Lancet, written by Dr Adnan I. Qureshi, (Zeenat Qureshi Stroke Research Center, University of Minnesota, USA); Dr A David Mendelow (University of Newcastle, UK); and Dr Daniel F Hanley (Johns Hopkins Medical Institutions, Baltimore, USA).
Labs Are Vital™ announced that a 2009 high school graduate from northern California, Kelly Peterson, is the grand prize winner of its national video contest. High school students around the country submitted their views on video about why careers in the clinical lab sciences are vital.
Feeling stressed? Then try savoring the scent of lemon, mango, lavender, or other fragrant plants. Scientists in Japan are reporting the first scientific evidence that inhaling certain fragrances alter gene activity and blood chemistry in ways that can reduce stress levels. Their study appears in ACS" Journal of Agricultural and Food Chemistry, a bi-weekly publication.
The American College for Advancement in Medicine (ACAM) has released its position regarding HB 3200, the health care reform bill proposed by the Obama administration. While ACAM believes healthcare reform is vital and necessary for America, it is our position that integrative medicine principles be included to yield the desired result of creating a more efficient, wellness-centered approach to healthcare.
Over the last four years, heart specialists at NewYork-Presbyterian Hospital/Columbia University Medical Center have implanted an innovative aortic heart valve replacement using a catheter-based approach that does not require open-heart surgery in a total of 100 patients -- the most of any U.S. medical center to date.
Dr. Donald Palmisano, former president of the American Medical Association and current spokesman for the Coalition to Protect Patients" Rights (Coalition) and over forty doctors from across the country today urged Members of Congress to slow down health system reform and do it right. The Coalition held a press conference at the National Press Club to urge legislators to put patients first when developing a system overhaul.
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, has announced that a study published online in the peer-reviewed journal Child and Adolescent Psychiatry and Mental Health found once-daily Vyvanse® (lisdexamfetamine dimesylate) CII significantly reduced the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 from the first time point measured (1.5 hours) up to the last time point assessed (13 hours) after administration. In this pediatric analog classroom study, treatment with Vyvanse was associated with significant improvement in behavior and attention in children at each time point measured, with improvement at 13 hours after administration.
Scientists have launched a project to make hair dye out of seaweed from around the Shetland Islands.
Foot & Ankle Specialist (FAS), published by SAGE, has been accepted for inclusion in MEDLINE, the premier bibliographic database of the U.S. National Library of Medicine (NLM), containing more than 16 million journal article citations.
Psychopharmaceutical use has risen over recent years. This is fact, but what is not clear is the reason why. Researchers from four Madrid-based health centres have shown that family conflict is not a significant factor. However, the results published in the journal AtenciÃön Primaria are striking: in Spain, 24% of women take antidepressants and more than 30% take tranquillisers.
A high intake of linoleic acid, a common dietary polyunsaturated fatty acid (N-6 PUFA), might be implicated in a third of ulcerative colitis cases, suggests research published ahead of print in Gut.
The American Lung Association applauds the Food and Drug Administration for its announcement about e-cigarettes. FDA"s preliminary findings show e-cigarettes contain carcinogens and toxic chemicals, including ingredients found in antifreeze.
The European Medicines Agency has been formally notified by Gendux
The National Changing Diabetes((R)) Program (NCDP), a program of Novo Nordisk, and several member associations today urged President Obama and members of Congress to make the prevention, detection and treatment of diabetes, one of the nation"s most pervasive and costly diseases, a priority in reforming the U.S. healthcare system.
Ozone exposure, even at levels deemed safe by current clean air standards, can have a significant and negative effect on lung function, according to researchers at the University of California Davis.
University of Utah researchers and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumor called paraganglioma (PGL). The gene, called hSDH5, is required for activation of an enzyme complex that plays a critical role in the chemical reactions that take place within cells to convert biochemical energy into usable energy. This study is published in the journal Science
"With many Americans growing anxious about his plans to overhaul the nation"s healthcare system, President Obama on Wednesday sought to lay out in personal terms how they stand to gain from the legislation that he has made one of the top goals of his presidency," the Los Angeles Times reports. He used the speech to reach out to people who already have insurance, arguing that skyrocketing costs must be slowed and that inaction would hobble businesses and families alike. In making the case for health reform to the American public, however, Obama described specific policy ideas and "relied on jargon that Washington insiders embrace but that might leave the typical television viewer mystified" (Nicholas, Parsons and Levey, 7/23).
Sen. Orrin Hatch, R-Utah, removes himself from Sen. Max Baucus"s bipartisan health reform talks in the Senate Finance Committee, leaving six centrist senators in what used to be called "the coalition of the willing." And, Senate Majority Whip Dick Durbin, D-Ill., says President Barack Obama"s August deadline is unworkable.
Researchers at The University of Nottingham are hoping to find out if inflammation of the knee could be an early sign of osteoarthritis - a condition which leads to pain, stiffness, swelling and disability.
Case Western Reserve University School of Medicine has received a $3.7 million grant from the National Institutes of Health to determine if painful bladder syndrome may be caused by abnormalities in the autonomic nervous system rather than in the bladder itself.
Two papers published on bmj.com today raise serious concerns over the methods used to put a value on the benefits of different treatments in order to set healthcare priorities.
An event to mark the celebrate the 10th anniversary of the UQ Ipswich Campus and the launch of UQ"s teaching of Medicine at UQ Ipswich will be held today, Friday, July 24, 2009.
People with potentially "stigmatizing" medical conditions are just as likely as those with less stigmatizing illnesses to allow their personal information to be used for health research. A new study, published in the open access journal BMC Medical Ethics, found that the purpose of the research and the type of information to be collected were more important in determining patients" consent choices. In particular, they were very wary of allowing their personal information to be put to commercial use.
Heritage Place, a UPMC Senior Community, has been awarded Activity Department of the Year for 2009 by the National Certification Council for Activity Professionals.
Orexo"s (STO:ORX) partner in Japan, Kyowa Hakko Kirin, has obtained positive phase III results in Japan for KW-2246, which is approved for the treatment of breakthrough pain in cancer patients and marketed under the brand AbstralTM in Europe. Kyowa Hakko Kirin will now proceed with preparations for a new-drug application for KW-2246 in Japan for use in continuous pain management of acute cancer pain (breakthrough pain).
Designed to boost the immune system and promote health, probiotics are gaining popularity at the grocery, and Nevella® with Probiotics, made by Heartland Sweeteners, is the first and only such sweetener currently on the market. Diabetes educators will get an early preview of Nevella® with Probiotics at their annual conference in Atlanta in early August, immediately prior to widespread availability across the country.
When Tony Goldberg is not whacking through the brush of central
Five Yale School of Medicine investigators have received of new Pilot Project Program grants from Women"s Health Research at Yale. They will study a variety of women"s health areas and gender differences that affect disease and behavior.
Expectant mothers who are obese are much more likely to suffer from minor complications such as heart burn and chest infections during pregnancy, a study suggests.
Most Canadians with chronic conditions have a regular place of care, but there are some reported gaps in the management of their conditions according to a new study released today by the Canadian Institute for Health Information (CIHI). The study, Experiences With Primary Health Care in Canada, measures access to and quality of care from a patient perspective across Canada"s 10 provinces. The study is based on the responses of more than 11,000 people age 18 and older to Statistics Canada"s 2008 Canadian Survey of Experiences With Primary Health Care, which was jointly funded by CIHI and the Health Council of Canada.
Aradigm Corporation (OTCBB:ARDM) (the "Company") announced it received clearance from the U.S. Food and Drug Administration (FDA) for its inhaled liposomal ciprofloxacin Investigational New Drug (IND) application. The initial clinical protocol under this IND is an international, randomized, double-blind, placebo-controlled Phase IIb study designed to evaluate the Company"s inhaled liposomal ciprofloxacin in patients with non-cystic fibrosis bronchiectasis (BE). This orphan drug condition is a chronic severe respiratory disease and there is currently no drug specifically approved for its treatment in the U.S.
VistA Imaging, the medical and health care imaging system used in Department of Veterans Affairs (VA) medical centers, attained over one billion stored images in January this year, according to the department.
Breathing xenon gas can help protect the infant brain from damage caused by oxygen deprivation, but the xenon"s high cost and scarcity has precluded its widespread use. A newly developed "closed circuit system" may make xenon feasible, safe, and cost efficient for use in protecting the brains of critically ill infants, according to a study in the August issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, pharmacy and the pharmaceutical industry.
Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) and its wholly owned subsidiary, BiPar Sciences, announced the initiation of the pivotal Phase III trial for BSI-201 in combination with chemotherapy in patients with metastatic triple-negative breast cancer (mTNBC), defined by tumors lacking expression of estrogen, progesterone receptors and without over-expression of HER2. BSI-201 is a novel investigational targeted therapy which inhibits poly (ADP-ribose) polymerase (PARP1), an enzyme involved in DNA damage repair.
The U.S. Agency for International Development funded programs that used biblical lessons to promote sexual abstinence in Africa, despite a prohibition on the use of taxpayer funds to support "inherently religious activities," according to a recent audit by the agency"s inspector general, the Washington Post reports.The audit focused on projects initiated from 2006 to 2007 during the administration of President George W. Bush. According to the audit, the use of Christian stories in HIV/AIDS prevention programs in Africa could be seen as showing a "USAID-funded preference for Christianity." The audit also found that officials in one faith-based abstinence program in Africa urged youth to memorize and recite a passage from the Bible"s book of Psalms. Participants were then instructed to recite the passage"s "key concept": "God has a plan for sex and this plan will help you and protect you from harm."USAID challenged the findings in a written response that said its African programs" main goals are secular in nature. It acknowledged that some of its abstinence programs included "religiously infused materials" but said that the materials showed no preference for Christian groups.According to the Post, the issue has been complicated by legal ambiguities over whether the separation of church and state applies to programs for promoting U.S. foreign policy abroad. The inspector general"s report said the Department of Justice is considering a request from USAID to determine the legality of its practices (Lynch, Washington Post, 7/23).
Various news outlets examined the powerful roles members of the Obama administration are taking in the health care debate.
A Web-based system allowing general practitioners to confer with specialists regarding patients with skin conditions may reduce referrals to dermatologists by approximately 20 percent, according to a report in the May issue of Archives of Dermatology, one of the JAMA/Archives journals.
Current treatment of cystic echinococcosis is surgery or percutaneous aspiration, injection and reaspiration (PAIR) using hypertonic saline or ethanol. It is aimed at causing permanent damage to the endocyst - the thin, delicate, and translucid inner membrane that produces the cystic fluid and generates new larval elements able to expand the infestation. Surgery and PAIR on liver and lung can result in biliary or bronchial fistulae, prompted by endocyst detachment; chemical cholangitis or pneumonia, due to passing of hypertonic saline or ethanol into the biliary or bronchial tree; and infection or abscess on the residual cyst cavity.
The air in Beijing during the 2008 Olympics was cleaner than the previous year"s, due to aggressive efforts by the Chinese government to curtail traffic, increase emissions standards and halt construction in preparation for the games, according to a Cornell study.
The Canadian Food Inspection Agency (CFIA), in collaboration with stakeholders, trading partners, and the public and animal health communities, has refined its approach to managing cases of the pandemic H1N1 2009 virus in swine.
The Federal Secretary of the Australian Nursing Federation, Ged Kearney and the Assistant Federal Secretary, Lee Thomas will be available for comment on the Prime Minister"s address on the challenges of Health Reform and the release of the NHHRC report.
UCB announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has issued a positive opinion recommending that the European Commission grant marketing authorisation for Keppra® as adjunctive treatment of partial-onset seizures in infants and young children aged one month to under four years.
Researchers are hoping that cells from pigs from a remote group of islands 300 miles from New Zealand could lead to a new treatment for Type 1 diabetes.
In recent years, oncologists have debated whether patients with a certain type of advanced lung cancer would benefit from surgery.
The Minister for Health and Children, Mary Harney TD, welcomed the publication of the report of the independent audit of retained organs in the State by Michaela Willis.
MEDEC - Canada"s Medical Technology Companies - applauds the Ontario Government for its recent decision to add Positron Emission Tomography (PET) Technology to the services covered by the Ontario Health Insurance Plan (OHIP) thereby ensuring that Ontarians have access to PET technology.
Nanobiotix, an emerging nanomedicine company, announced exciting preclinical results using its patented nanoXray therapeutics platform to fight tumors. The preclinical study, performed at Institut Gustave Roussy, one of Europe"s leading cancer treatment centers, showed that an intratumoral injection of NBTXR3 nanoparticles and activated via standard radiation therapy led to complete tumor regression in mice at 60 days, compared to zero tumor regression in mice treated with xray only or NBTXR3 only. The study was led by principal investigator, Jean Bourhis, M.D., Ph.D. a prominent radiation oncologist and researcher at Institut Gustave Roussy.
Staff working in UK veterinary practices lack access to good occupational health advice warns a new study published in the scientific journal, Occupational Medicine. The research, the first published benchmark of occupational health risk management by vet practices in the UK, showed that despite veterinary surgeons and nurses being exposed to many occupational hazards less than a third of practices had trained staff in health and safety and only 14% sought advice from occupational health professionals.
An Article published Online First and in an upcoming edition of The Lancet concludes that radiotherapy plus chemotherapy, with or without surgery, are both treatment options for patients with stage IIIA (N2) non-small-cell lung cancer. The Article is written by Dr Kathy Albain, Loyola University Chicago Stritch School of Medicine, Cardinal Bernardin Cancer Center, Maywood, IL, USA, and colleagues.
A recent independent study has confirmed Fortoss Vital(R), developed by the Pioneering Orthobiologics Company, Biocomposites, as an effective bone replacement material demonstrating superior bone regenerative properties due to its unique negative zeta potential control (ZPC(TM)).
The health cost of obesity in the United States is as high as $147 billion annually, based on a new study from Research Triangle Institute and the Centers for Disease Control and Prevention. The study, which appears online today in the journal Health Affairs, was released at CDC"s Weight of the Nation conference in Washington, D.C.
Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNAi)-based therapeutics, announced data suggesting that QPI-1007 prevents progressive retinal ganglion cell (RGC) loss in an increased ocular pressure (IOP) rat model of glaucoma. The experiments performed by Prof. Adriana Di Polo of the Department of Pathology and Cell Biology, Universite de Montreal, indicate that QPI-1007 has the potential to treat patients with glaucoma. QPI-1007 is being evaluated in advanced IND-enabling preclinical studies as a neuroprotective agent for eye diseases.
Several news organizations have published lists to explain health care reform legislation.
"Health care groups working feverishly to shape -- or kill -- an industry-wide reform bill are lavishing campaign cash on the politicians at the center of the debate," The Salt Lake (Utah) Tribune reports. Sens. Orrin Hatch and Max Baucus, both major health reform players on the Senate Finance Committee, are among those benefiting form the uptick in contributions. One lobbyist for the watchdog group Public Citizen said, "A person can reach no other conclusion than this is quid pro quo activity" (Canham, 7/27).
The Health-Care Sacrifice The Washington Post
The Journal of Clinical Oncology (DOI: 10.1200/JCO.2008.20.2515) releases an article covering Active Biotech"s (NASDAQ OMX Nordic: ACTI) cancer project ANYARA, where ANYARA was studied both as a single agent and in combination with an established tumor therapy - docetaxel (Taxotere®) - in patients with advanced cancer.
The AMA has congratulated the National Health and Hospitals Reform Commission on its final report launched in Canberra by Prime Minister Kevin Rudd.
Six University of Alabama at Birmingham (UAB) students and two students from other universities are using satellite imagery to identify possible habitats in Alabama for the black-legged tick that carries and transmits Lyme disease.
A new report, "The Intelligent Board 2009: Commissioning to reduce inequalities", produced by an independent reference group of experts, encourages Primary Care Trust (PCT) Boards to review their understanding of health inequalities in their communities so that they can be addressed.
The appropriate placement of automated external defibrillators (AEDs) is critical to optimize their use in public places, according to two studies published in Circulation: Journal of the American Heart Association.
For the 29,000 patients in the United States with metastatic colorectal cancer, chemotherapy with irinotecan is a standard treatment that has been shown to improve survival. But for more than one in 10 of these patients, a variation in their DNA means that this treatment could result in a severe reduction in their white blood cell count, leading to a high risk of bacterial infection and possible subsequent death. A new genetic test can identify those with the variation in order to lower the treatment dose - however, it has been unclear whether the testing is worthwhile.
Accumulation of the synaptic protein alpha-synuclein, resulting in the formation of aggregates called Lewy bodies in the brain, is a hallmark of Parkinson"s and other related neurodegenerative diseases. This pathology appears to spread throughout the brain as the disease progresses. Now, researchers at the University of California, San Diego School of Medicine and Konkuk University in Seoul, South Korea, have described how this mechanism works. Their findings - the first to show neuron-to-neuron transmission of alpha-synuclein - will appear in the Proceedings of the National Academy of Sciences (PNAS) on July 29.
The Lymphoma Research Foundation (LRF) is pleased to announce that the 2009 Millennium Pharmaceuticals, Inc./Lymphoma Research Foundation Clinical Investigator Career Development Award has been awarded to Kai Fu, MD, PhD, Associate Professor at the Nebraska Medical Center in Omaha, Nebraska.
Committees in the New Jersey Senate and Assembly on Monday unanimously approved a bill that would provide insurance benefits of up to $36,000 annually for autism treatments, the Philadelphia Inquirer reports. The funding, provided to developmentally disabled individuals younger than age 21, would go toward diagnostic services and early behavioral intervention, as well as occupational, physical and speech therapies. The Assembly could vote on the bill as early as Thursday, while the Senate bill is being considered by the state Senate Budget and Appropriations Committee.Sen. Loretta Weinberg (D), who sponsored the Senate bill, said, "I don"t know of any parent who wouldn"t do everything in their power to give their autistic or developmentally disabled child every chance to excel. However, the enormous cost of behavior intervention ... makes it out of the realm of possibility for many families." Assembly Speaker Joseph Roberts (D), who sponsored the Assembly bill, said, "In this economy, every New Jersey resident is struggling, but families with kids with special needs are struggling even more," adding, "They"re maxing out their credit cards and taking out second mortgages" to cover gaps in health insurance benefits.Citing cost issues, the New Jersey Business and Industry Association and the New Jersey Association of Health Plans were among those opposed to the bill. Christine Stearns, NJBIA vice president for health and legal affairs, said that the bill would make employer-sponsored insurance more costly and cause firms to drop such coverage, adding, "How, who and what is part of a basic health plan is all part of that." Stearns added that the bill is preferable to previous versions because it mandates that covered services be medically necessary and prescribed, places a reasonable cap on prices and ensures that the cost of educational services provided by schools is not shifted to insurers. Roberts said the bill would save money by delivering earlier treatment that could prevent more costly problems in the future (Henry, Philadelphia Inquirer, 5/19).
The Vermont Legislature has passed legislation (S 48) that bans nearly all gifts from pharmaceutical and medical device companies to health care providers, administrators and facilities in the state, the New York Times reports. The legislation specifically would prohibit drug and device makers from giving providers no-cost meals. Vermont"s legislation would go further than similar laws in other states like Massachusetts and Minnesota by requiring drug and medical device manufacturers who give gifts to health providers to publicly disclose recipients" names and dollar amounts of payments and gifts. The measure would not require manufacturers to disclose payments for clinical research of products undergoing FDA review, the Times reports. The legislation also would eliminate a loophole that allows manufacturers to conceal certain expenses by claiming them as trade secrets. In a recent report, the Vermont Office of the Attorney General said that medical product makers spent about $2.9 million on promotional efforts to the state"s health care providers in fiscal year 2008 and that nearly half of the state"s 4,573 licensed providers had received some type of incentive from drugmakers in the same year. The report, which was developed prior to passage of the new legislation, offers only aggregate data, as 83% of the manufacturer-declared payments were deemed to be trade secrets, the Times reports.Gov. Jim Douglas (R) is expected to sign the law, which would take effect July 1. Several state medical groups -- including the Vermont Association for Mental Health and the Vermont Medical Society -- have indicated support for the legislation.Marjorie Powell, a senior lawyer for the Pharmaceutical Research and Manufacturers of America, said the requirements under the new law appear redundant with new voluntary guidelines the group has issued on physician gifting practices. She said, "We think this is unnecessary, and it is not going to improve patient care," adding, "It makes it onerous not only for the company but also for the physician in Vermont, because this is going to be on a Web site" (Singer, New York Times, 5/20).
A team of astronomers has discovered a group of rare galaxies called the "Green Peas" with the help of citizen scientists working through an online project called Galaxy Zoo. The finding could lend unique insights into how galaxies form stars in the early universe.
Health care leaders focused on changing their organization"s approach to patient safety and quality will have an opportunity to learn from their peers at The Joint Commission and Joint Commission Res" "2009 Annual Conference on Quality and Patient Safety: Explore, Enhance, and Energize - Leadership for the Future." The conference, September 14 to 16, in Rosemont, Ill., is supported by the American Hospital Association, the American Medical Association and the American College of Physicians. Joint Commission Res (JCR) is a not-for-profit affiliate of The Joint Commission.
÷£25 million announced to more than treble the number of NHS apprenticeships