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A Tiny Frozen Microbe May Hold Clues To Extraterrestrial Life
A novel bacterium that has been trapped more than three kilometres under glacial ice in Greenland for over 120 000 years, may hold clues as to what life forms might exist on other planets.
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Meeting Addresses MTCT Of HIV In Africa
Health officials recently held a regional consultation in Kenya to examine mother-to-child HIV transmission services and pediatric HIV/AIDS care in nine Eastern and Southern African countries, IRIN/PlusNews reports. The consultation -- hosted by UNICEF, UNAIDS and the World Health Organization -- included representatives from Ethiopia, Kenya, Malawi, Mozambique, South Africa, Swaziland, Tanzania, Uganda and Zambia. The meeting addressed issues in MTCT prevention services -- including the continued use of single-dose nevirapine instead of more effective combination therapies, as well as delays in diagnosing and initiating treatment -- that are weakening prevention programs in focus countries. According to IRIN/PlusNews, 70% of pregnant women in Eastern and Southern African countries are seen by a health care provider at least once during pregnancy. However, 43% of HIV-positive pregnant women have a health care worker present during labor who can administer PMTCT treatment. In Uganda, a national policy calls for all sub-county level health facilities to provide PMTCT services, but only 53% offer such services because of health worker shortages. Janet Kayita, regional PMTCT adviser for UNICEF, said, "We are doing a bad job of testing women for HIV and then following them up, and an even worse job of ensuring that infants receive appropriate prevention and treatment services." She added that national PMTCT guidelines have not reached local levels. "These policies must become a reality for the people they were designed to help," Kayita said, adding that primary health care systems at all levels must be strengthened (IRIN/PlusNews, 5/25).Some officials at the meeting called on African governments to reach 80% of pregnant women, mothers and children with services; reduce by 50% the number of women and infants who do not receive follow-up care; and double the number of HIV-positive children who receive antiretroviral treatment. Xinhuanet reports that prevention services currently reach about 50% of pregnant women in all Eastern and Southern African countries. At the close of the consultation, officials issued a set of recommendations for meeting PMTCT goals, including increased community involvement in prevention programs; reduced workloads for health workers; and increased coverage of and compliance with PMTCT regimens. In addition, the experts urged governments to prioritize regions with high HIV burdens and strengthen data management to better understand trends (Ooko, Xinhuanet, 5/25). James Kamau, coordinator of the Kenya Treatment Access Movement, recommended that more women in the country deliver in hospitals in order to ensure that they receive PMTCT services (Mwaniki, Daily Nation, 5/25). David Alnwick, a UNICEF regional adviser, said, "It is critical at this juncture, when many countries are faced with shrinking budgets and competing demands, that we do not lose the momentum of what needs to be done to create an AIDS-free generation" (Xinhuanet, 5/25).
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Tapentadol Tablets For Moderate To Scute Pain In Over 18s Now Available For Use In The United States
German pain expert company GrÃønenthal GmbH announces that the new centrally acting analgesic tapentadol is now available in the United States. The drug is indicated for the relief of moderate to severe acute pain in patients 18 years of age and older. Approval was given by the US Food and Drug Administration (FDA) in November 2008 for tapentadol (NUCYNTATM) tablets. With the cooperation of GrÃønenthal and its marketing partner Ortho-McNeil-Janssen Pharmaceuticals, Inc., the medication can now be prescribed by physicians and other appropriate health care professionals in the United States.
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Women With Chest Pain Less Likely Then Men To Get Proper Treatment From Paramedics

Women with chest pain are less likely than male patients to receive recommended, proven therapies while en route to the hospital, according to new research from the University of Pennsylvania School of Medicine. Despite evidence showing that the drugs aspirin and nitroglycerin are important early interventions for people who may be having a heart attack, women don"t get them as often as male patients with the same types of symptoms, says a new study that will be presented Friday, May 15, 2009 at the Society for Academic Emergency Medicine"s annual conference. While the researchers found no differences in the types of care given by emergency medical service (EMS) providers to African-American and white patients, they are troubled by the evidence that women may be receiving sub-optimal care, and say it highlights the need for pre-hospital providers to be sensitive to the fact that women may have atypical symptoms. Since chest pain is a leading cause of emergency room visits in the United States, accounting for more than 8 million visits a year, the implications of the findings are broad. "Women with heart attacks have higher death rates than men, so these findings are very concerning, and it"s important for us to try to figure out why this is happening," says lead author Zachary Mesiel, MD, MPH, an emergency physician and Robert Wood Johnson Foundation Clinical Scholar and Senior Fellow at the Leonard Davis Institute of Health Economics at Penn. Heart attack damage takes place gradually, as portions of the heart muscle are deprived of oxygen over several hours. Early interventions like aspirin therapy -- which reduces clotting around the ruptured coronary plaques that grow to block blood flow to the heart -- play an important role in preventing damage to this cardiac tissue. Recent national efforts underscore the maxim that in treatment of heart attacks, "time is muscle." Many EMS organizations, for instance, have outfitted ambulances with cardiac monitoring equipment that can send information about a patient"s heart rhythm ahead to the hospital so the cardiac catheterization lab can be alerted to prepare for a patient who will need prompt treatment to open their blocked arteries. Initiatives like these have helped hospitals to reduce their so-called "door-to-balloon time," which describes the minutes between when the patient arrives at the hospital and is sent to the cardiac cath lab. The time patients spend being cared for by EMS personnel in the field or in an ambulance is also a vital part of that chain of care, so Meisel and his colleagues say emergency responders should strive to implement best practices for all chest pain patients. The new Penn study examined 683 cases in 2006 and 2007 in which EMS was summoned for a complaint of chest pain and brought patients to one of three Philadelphia hospitals in the University of Pennsylvania Health System. The authors examined the frequency with each patients received four key EMS treatment and monitoring protocols which are called for in for chest pain patients over the age of 30. The measures included whether patients got aspirin and nitroglycerin, which relieves cardiac pain, and whether they received heart rhythm monitoring or had IV lines placed to begin medication delivery. Results showed that women were significantly less likely than men to receive aspirin while in the care of EMS 24 percent of them were given the drug, compared to 32 percent of men. Twenty-six percent of women got nitroglycerin, compared to 33 percent of men, and 61 percent of women had an IV line placed, compared to 70 percent of men. Women who ultimately were found to be having a heart attack upon arrival the emergency department were also significantly less likely to have received those treatments and interventions while being transported by EMS in fact, none of them received pre-hospital aspirin. Even after the researchers adjusted for the possibility that age, race, and baseline medical risk could have played a role in these apparent disparities, the gender gaps in adherence to care protocols still remained. The gender of the medic involved in the case also did not appear to change the findings. Previous studies have revealed gender disparities in diagnosis and treatment of chest pain and cardiac conditions in both inpatient and outpatient settings, partially because women"s heart problems often present in uncommon ways that may be attributed to other, less severe illnesses or injuries. These same differences in symptoms could also account for the differences seen in the new study. "I suspect some of the treatment differences between men and women may be related to differences is the way the chest pain symptoms are interpreted, both by the providers and by the patients themselves," Meisel says. "So if you are a patient, it"s important to be direct and clear about your symptoms to all your medical providers -- even if it feels like you are telling the same story over and over again." PENN Medicine is a $3.6 billion enterprise dedicated to the related missions of medical education, biomedical research, and excellence in patient care. PENN Medicine consists of the University of Pennsylvania School of Medicine (founded in 1765 as the nation"s first medical school) and the University of Pennsylvania Health System. Penn"s School of Medicine is currently ranked #3 in the nation in U.S.News & World Report"s survey of top research-oriented medical schools; and, according to the National Institutes of Health, received over $366 million in NIH grants (excluding contracts) in the 2008 fiscal year. Supporting 1,700 fulltime faculty and 700 students, the School of Medicine is recognized worldwide for its superior education and training of the next generation of physician-scientists and leaders of academic medicine. The University of Pennsylvania Health System (UPHS) includes its flagship hospital, the Hospital of the University of Pennsylvania, rated one of the nation"s top ten "Honor Roll" hospitals by U.S.News & World Report; Pennsylvania Hospital, the nation"s first hospital; and Penn Presbyterian Medical Center, named one of the nation"s "100 Top Hospitals" for cardiovascular care by Thomson Reuters. In addition UPHS includes a primary-care provider network; a faculty practice plan; home care, hospice, and nursing home; three multispecialty satellite facilities; as well as the Penn Medicine at Rittenhouse campus, which offers comprehensive inpatient rehabilitation facilities and outpatient services in multiple specialties. University of Pennsylvania School of Medicine


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