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Chair Of General Pharmaceutical Council Is Welcomed By Society
The Royal Pharmaceutical Society of Great Britain (RPSGB) has welcomed the appointment of Mr Robert Nicholls CBE as the Chair Designate of the General Pharmaceutical Council (GPhC).
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House Seeks To Pay For Reform With New Tax On Wealthy
House Democrats are expected to begin marking up a health reform bill this week that members of the Ways and Means committee said "would cost less than $1 trillion over 10 years, [and would be] paid for chiefly by a combination of spending reductions in the health care system and a surtax on wealthy taxpayers," CQ Politics reports. "The surtax would be levied beginning in 2011. ò€¦ [T]here would be three income brackets - $350,000, $500,000 and $1 million for couples filing jointly, and $280,000, $400,000 and $800,000 for individuals - with a different rate at each level: "One, two, three [percent] - something like that,"" the committee"s chairman, Charles Rangel, D-N.Y., said (Wayne, 7/13).
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KPBS Examines San Diego County Board Of Supervisors' Opposition To Needle Exchange Program
KPBS examines the reasons why the San Diego Board of Supervisors will not support the city"s needle exchange program, which twice weekly provides clean needles to injection drug users as part of an effort to curb the spread of HIV, Hepatitis C and other blood-borne diseases. Dianne Jacob, chair of the board, said, "I think it particularly sends a wrong message to our kids. It sends a message to our kids that as county government, if we gave out clean needles for illegal drug use, that we condone illegal drug use. And we don"t. And it"s wrong." She said government support should go toward drug use prevention and treatment. Steffanie Strathdee, head of the division of global public health at the University of California-San Diego School of Medicine, has examined several needle exchange programs across the world, and said, "It hasn"t been associated with more people starting drug use at earlier ages, etc., ò€¦ In fact, it"s consistently been associated with reductions in high-risk behavior. And so there"s really no reason not to support it on a broader scale" (Goldberg, 7/8). This series of articles was supported by a Kaiser Family Foundation mini reporting fellowship.
Nutrition

Progress Toward Artificial Tissue

For modern implants and the growth of artificial tissue and organs, it is important to generate materials with characteristics that closely emulate nature. However, the tissue in our bodies has a combination of traits that are very hard to recreate in synthetic materials: It is both soft and very tough. A team of Australian and Korean researchers led by Geoffrey M. Spinks and Seon Jeong Kim has now developed a novel, highly porous, sponge-like material whose mechanical properties closely resemble those of biological soft tissues. As reported in the journal Angewandte Chemie, it consists of a robust network of DNA strands and carbon nanotubes. Soft tissues, such as tendons, muscles, arteries, and skin or other organs, obtain their mechanical support from the extracellular matrix, a network of protein-based nanofibers. Different protein morphologies in the extracellular matrix produce tissue with a wide range of stiffness. Implants and scaffolding for tissue growth require porous, soft materials -- which are usually very fragile. Because many biological tissues are regularly subjected to intense mechanical loads, it is also important that the implant material have comparable elasticity in order to avoid inflammation. At the same time, the material must be very strong and resilient, or it may give out. The new concept uses DNA strands as a matrix; the strands completely "wrap" the scaffold-forming carbon nanotubes in the presence of an ionic liquid, networking them to form a gel. This gel can be spun: just as silk and synthetic fibers can be wet-spun for textiles, the gel can be made into very fine threads when injected into a special bath. The dried fibers have a porous, sponge-like structure and consist of a network of intertwined 50 nm-wide nanofibers. Soaking in a calcium chloride solution further cross-links the DNA, causing the fibers to become denser and more strongly connected. These spongy fibers resemble the collagen fiber networks of the biological extracellular matrix. They can also be knotted, braided, or woven into textile-like structures. This results in materials that are as elastic as the softest natural tissues while simultaneously deriving great strength from the robust DNA links. An additional advantage is the electrical conductivity of the new material, which can thus also be used in electrodes for mechanical actuators, energy storage, and sensors. For example, the researchers were able to produce a hydrogen peroxide sensor. The carbon nanotubes catalyze the oxidation of hydrogen peroxide, which results in a measurable current. Hydrogen peroxide plays a role in normal heart function and certain heart diseases. A robust sensor with elasticity similar to the heart muscle would be of great help in researching these relationships. Geoffrey M. Spinks Wiley-Blackwell


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